Gertrude Elion — Questions and answers

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What kind of path did Gertrude Elion want to take for discovering new medicines?

Choices

  1. One based on precise biochemical understanding, not just guessing. ✓
  2. One that only used trial-and-error, like before.
  3. One that made therapies more dangerous than the illness.
  4. One that focused on making drugs for the AIDS epidemic right away.

Answer: One based on precise biochemical understanding, not just guessing.

From page 1

What important building blocks of life did Gertrude Elion study closely?

Choices

  1. Fats and sugars.
  2. Purines and pyrimidines, which make up DNA and RNA. ✓
  3. Vitamins and minerals.
  4. Muscles and bones.

Answer: Purines and pyrimidines, which make up DNA and RNA.

From page 3

What does 'differential metabolism' mean for how Elion's drugs worked?

Choices

  1. They only helped cells with slow metabolic rates.
  2. They were equally harmful to all cells.
  3. They became active only in sick cells, attacking them while leaving healthy cells alone. ✓
  4. They made all cells start building more nucleic acids.

Answer: They became active only in sick cells, attacking them while leaving healthy cells alone.

From page 6

Besides leukemia, what other medical problems did Elion and Hitchings' drug design principles help with?

Choices

  1. Only skin rashes and headaches.
  2. Gout and preventing organ transplant rejection. ✓
  3. Making people run faster.
  4. Improving eyesight.

Answer: Gout and preventing organ transplant rejection.

From page 7

What major award did Gertrude Elion receive for her work in 1988?

Choices

  1. An Oscar for best scientist.
  2. A medal for bravery.
  3. The Nobel Prize in Physiology or Medicine. ✓
  4. A certificate for learning by herself.

Answer: The Nobel Prize in Physiology or Medicine.

From page 10