Jennifer Doudna — Questions and answers
What was the critical insight Jennifer Doudna and Emmanuelle Charpentier had that simplified the CRISPR system?
Answer: They realized two RNA molecules could be combined into one 'guide RNA'.
What happens when Cas9 finds a perfect match to its sgRNA next to the PAM sequence?
Answer: It creates a double-strand break in the DNA.
What major award did Jennifer Doudna and Emmanuelle Charpentier receive for their work on CRISPR-Cas9?
Answer: The Nobel Prize in Chemistry